Supporting gut epithelial regeneration
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چکیده
منابع مشابه
EGFR-dependent TOR-independent endocycles support Drosophila gut epithelial regeneration
Following gut epithelial damage, epidermal growth factor receptor/mitogen-activated protein kinase (EGFR/MAPK) signalling triggers Drosophila intestinal stem cells to produce enteroblasts (EBs) and enterocytes (ECs) that regenerate the gut. As EBs differentiate into ECs, they become postmitotic, but undergo extensive growth and DNA endoreplication. Here we report that EGFR/RAS/MAPK signalling i...
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ژورنال
عنوان ژورنال: Nature Reviews Microbiology
سال: 2018
ISSN: 1740-1526,1740-1534
DOI: 10.1038/s41579-018-0144-7